Profhilo
How Long Does Profhilo Last?
May 23, 2025
Research on skin regeneration has highlighted the potential of biomaterials and injectable hydrogels to enhance tissue repair and skin quality. These advancements aim to improve skin elasticity, hydration, and overall appearance by stimulating the skin’s natural regenerative processes. As the demand for long-lasting, non-invasive aesthetic treatments increases, patients are looking for solutions that deliver sustained results with minimal maintenance.
One such treatment is Profhilo, a breakthrough option designed to improve skin quality by delivering stabilized hyaluronic acid deep into the skin layers. Unlike traditional dermal fillers, Profhilo spreads evenly throughout the skin, stimulating collagen and elastin production, helping restore elasticity and hydration. The results are typically visible for several months, and maintenance sessions are recommended to prolong the effects.
In this article, we will explore the duration of Profhilo, its benefits, and the factors that influence its longevity, providing you with the information you need to make an informed decision about incorporating Profhilo into your skincare routine.
Key Takeaways
- Profhilo typically lasts between 6 to 9 months, though the duration can vary based on individual metabolism, age, and skin health.
- Visible improvements in skin hydration and firmness usually begin to show about four weeks after completing the initial two-session treatment.
- The treatment works gradually by stimulating collagen and elastin production, leading to natural-looking enhancements rather than dramatic changes.
- Regular maintenance sessions every 6 to 9 months are recommended to sustain the results and slow the signs of aging.
- Individuals with younger or healthier skin may experience longer-lasting benefits compared to those with more mature or damaged skin.
- Lifestyle habits such as smoking, dehydration, and excessive sun exposure can reduce the longevity of Profhilo’s effects.
- Profhilo can be safely combined with other aesthetic treatments like Botox, dermal fillers, microneedling, and laser resurfacing for enhanced results.
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Mechanism of Action and Duration
Profhilo works differently from traditional dermal fillers. Rather than adding volume or structure to the face, it uses high concentrations of hyaluronic acid to deeply hydrate the skin and stimulate collagen and elastin production. This process, known as bio-remodeling, enhances the skin’s firmness, elasticity, and overall quality by promoting natural skin regeneration.
Once injected, Profhilo spreads evenly under the skin and stimulates fibroblast activity. This biostimulatory effect continues for weeks after treatment, allowing the skin to gradually rejuvenate from within. On average, visible results begin to show within 2 to 4 weeks after the second session, and the effects typically last 6 to 9 months.
Unlike some treatments that offer instant results, Profhilo works gradually, offering a more natural and subtle improvement in skin texture and hydration. This means that the results fade subtly over time, rather than disappearing all at once, making it a great option for those seeking continuous improvement.
Factors Influencing Longevity
Several factors influence how long Profhilo lasts in each individual. Since the treatment doesn’t have a one-size-fits-all outcome, understanding these variables is essential to setting realistic expectations:
- Age: Older patients may metabolize hyaluronic acid more quickly and have slower collagen production, shortening the effects.
- Skin Condition: Healthier, more elastic skin tends to respond better and retain results longer.
- Lifestyle Habits: Smoking, alcohol use, and sun exposure can accelerate skin aging and reduce longevity.
- Metabolism: Individuals with faster metabolic rates may break down hyaluronic acid sooner.
- Hydration and Skincare: Proper hydration and skincare maintenance can help prolong the effects.
These factors highlight the importance of a tailored treatment plan and a maintenance schedule that aligns with an individual’s unique skin condition and lifestyle.
Maintenance and Repeat Treatments
To sustain Profhilo’s skin-rejuvenating benefits, regular maintenance sessions are essential. Most aesthetic providers recommend a follow-up treatment after several months. The initial phase typically involves two injections, spaced four weeks apart, which builds the foundation for lasting hydration and skin improvement. After completing this phase, the frequency of maintenance sessions will depend on the individual’s skin response and aging factors.
A typical maintenance schedule looks like this:
- Initial phase: 2 injections, 4 weeks apart
- Maintenance phase: 1 injection every 6–9 months
For individuals with more mature or damaged skin, an additional third session during the initial phase may help enhance results. Regular maintenance treatments prevent the skin from reverting to its pre-treatment condition, allowing the benefits to persist. As Profhilo can be paired with other treatments like microneedling or laser resurfacing, incorporating such therapies into the regimen can further accelerate visible skin rejuvenation.
Combining Profhilo with Other Treatments
When considering Profhilo vs Rejuran, it’s important to note that Profhilo works well in combination with other aesthetic treatments. Unlike traditional dermal fillers, which add volume to the face, Profhilo improves skin quality by enhancing hydration and elasticity without increasing volume. This makes it an ideal complement to other treatments aimed at skin rejuvenation or facial volumization.
- Dermal Fillers: Often paired with Profhilo to restore facial volume and enhance contours, while Profhilo improves skin quality and hydration overall.
- Botox: Effectively smooths dynamic lines, especially around the eyes and forehead, while Profhilo works to improve skin elasticity and surface texture.
- Microneedling or RF Treatments: Boosts collagen remodeling at deeper layers; combining with Profhilo enhances hydration and accelerates visible skin rejuvenation outcomes.
- Laser Skin Resurfacing: Targets pigmentation and fine lines; Profhilo supports skin recovery by boosting hydration and elasticity during the post-laser healing phase.
By combining Profhilo with other treatments, clinicians can achieve more comprehensive, synergistic results that enhance both skin health and appearance.
Conclusion
Profhilo offers a unique approach to skin rejuvenation by enhancing skin quality rather than simply reshaping it. Its gradual effects typically last between 6 to 9 months, depending on factors such as age, skin health, and lifestyle. While the results develop over time, regular maintenance treatments are essential for preserving the benefits and keeping your skin looking its best.
When combined with a healthy skincare routine and possibly other aesthetic treatments, Profhilo can significantly contribute to long-term skin health and vitality. As always, consulting with a licensed practitioner is crucial to determine the most suitable treatment plan for your specific skin needs and goals.
FAQs
1. What is Profhilo used for?
Profhilo is used to improve skin hydration, elasticity, and firmness, especially on the face, neck, and hands.
2. How is Profhilo different from traditional fillers?
Unlike fillers that add volume, Profhilo spreads beneath the skin to stimulate collagen and elastin without altering facial shape.
3. Is the treatment painful?
Most patients report mild discomfort. A topical anesthetic is usually applied to reduce any pain during the injection.
4. How soon will I see results?
Results typically become visible within 2 to 4 weeks after the second session, with continued improvement.
5. Are there any side effects?
Side effects are minimal and may include temporary redness, swelling, or bruising at the injection sites.
6. Who is a good candidate for Profhilo?
Adults showing signs of skin laxity or dryness who want natural-looking results without adding volume are ideal candidates.
7. Can Profhilo be used with other treatments?
Yes, it pairs well with Botox, fillers, microneedling, and lasers when managed under a professional skincare plan.
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References
Olteanu G, Sorinel Marius Neacșu, Florin Alexandru Joița, et al. Advancements in Regenerative Hydrogels in Skin Wound Treatment: A Comprehensive Review. International journal of molecular sciences. 2024;25(7):3849-3849. doi:https://doi.org/10.3390/ijms25073849
Sionkowska A, Katarzyna Lewandowska, A. Planecka, et al. Biopolymer Blends as Potential Biomaterials and Cosmetic Materials. Key engineering materials. 2013;583:95-100. doi:https://doi.org/10.4028/www.scientific.net/kem.583.95
