Profhilo
Published by Andrea Stearns
Last Updated On June 2, 2025

Profhilo Side Effects – The Complete List

May 25, 2025

Skin elasticity plays a crucial role in maintaining a youthful and healthy appearance. Research has found that biological elasticity declines significantly with age. This loss of elasticity leads to sagging, wrinkles, and reduced skin firmness, making it a key concern in anti-aging treatments.

One such treatment gaining popularity is Profhilo, an injectable hyaluronic acid-based product designed to improve skin hydration and elasticity. While praised for its ability to enhance skin texture and firmness, Profhilo is not without side effects. Understanding these potential reactions is essential for making informed decisions about skin treatments.

In this article, we will explore the complete list of Profhilo side effects, helping you weigh the benefits and risks before considering this treatment.

Key Takeaways

• Profhilo side effects are generally mild and temporary, commonly including redness, swelling, tenderness, bruising, and mild itching at injection sites.
• Serious side effects, such as allergic reactions, infections, nodules, vascular occlusion, or skin necrosis, are rare but require immediate medical attention.
• Careful patient selection and adherence to proper injection techniques significantly reduce the risk of complications and improve safety.
• Patients should follow post-treatment care recommendations, such as avoiding contact with the treated area, engaging in strenuous activity, and using gentle skincare products, to support healing and minimize side effects.
• Transparent communication between healthcare providers and patients regarding side effects and expectations is crucial for treatment satisfaction and adherence.

About: Trusted by over 2,000+ global clients since 2014, Maylips has become a leading supplier of cosmetic, skincare, and orthopedic products for medical and aesthetic professionals. Maylips offers a wide range of authentic brand-name products at competitive wholesale prices, sourced from around the world. If you’re looking to buy Profhilo online, contact our sales team for guidance.

Common Side Effects

Most people experience mild and temporary side effects after Profhilo injections. These are expected and usually resolve without any intervention. Common side effects typically occur at the points where the product is injected under the skin.

• Redness: Temporary redness at the injection sites is common and usually fades within a few hours.
• Swelling: Mild swelling may develop around treated areas, especially the face or neck, and generally subsides in 1–2 days.
• Tenderness: Treated areas may feel slightly tender to the touch for up to 48 hours.
• Bruising: Small bruises may form due to minor damage to blood vessels, but they typically heal within several days.
• Itching or Irritation: Some patients report itching, which is generally mild and short-lived.
• Lumpiness or Bumps: Small lumps under the skin may appear but usually smooth out as the product spreads.

These reactions are considered part of the body’s natural response to injections and are not cause for concern unless they persist or worsen.

Rare and Serious Side Effects

While uncommon, some side effects may require immediate medical attention. Though rare, it’s important to be aware of these potential complications:

• Allergic Reaction: Symptoms may include a rash, itching, swelling that extends beyond the injection site, or difficulty breathing.
• Infection: If aseptic technique is not followed, bacterial infections may develop, resulting in redness, warmth, and the presence of pus.
• Nodule Formation: Hard lumps or granulomas may form under the skin in rare cases.
• Vascular Occlusion: Accidental injection into a blood vessel can restrict blood flow, leading to skin discoloration and tissue damage.
• Persistent Swelling or Pain: Ongoing discomfort may indicate an underlying complication that requires medical review.
• Skin Necrosis: Extremely rare but serious, this occurs when the blood supply to tissue is compromised.

Immediate consultation with a healthcare professional is advised if any of these symptoms develop after Profhilo treatment.

Patient Selection and Risk Mitigation

When considering and comparing similar injectable skin treatments like Profhilo vs Jalupro, careful patient selection and proper technique are essential to minimize side effects and ensure safe, effective results tailored to individual skin needs and aesthetic goals. Key considerations include:

• Medical History Review: Screen for allergies, autoimmune conditions, or recent infections.
• Medication Check: Identify use of blood thinners, immunosuppressants, or recent use of other injectables.
• Skin Assessment: Evaluate the skin condition and avoid treating infected or inflamed areas.
• Proper Hygiene: Maintain sterile techniques during the procedure to prevent infection.
• Injection Technique: Use the recommended bio-aesthetic points and depth to avoid complications.
• Patient Expectations: Discuss likely outcomes and side effects clearly to avoid anxiety post-procedure.
• Avoid in Pregnancy/Breastfeeding: Profhilo is not recommended during these periods due to limited safety data.

Selecting appropriate candidates and following strict clinical protocols helps ensure optimal results with minimal side effects.

Post-Treatment Care and Monitoring

Aftercare is crucial in reducing side effects and ensuring a comfortable recovery. Most post-treatment issues can be managed with simple at-home care. Essential steps include:

• Avoid Touching or Massaging the Area: Let the product settle naturally for at least 6–8 hours.
• Skip Strenuous Activity: Avoid intense exercise, saunas, or hot showers for 24–48 hours.
• Stay Upright: Keep your head elevated and avoid lying down for the first few hours.
• Avoid Alcohol and Blood Thinners: These may increase the chance of bruising.
• Apply a Cold Compress if Needed: This can help minimize swelling or discomfort.
• Use Gentle Skincare Products: Avoid active ingredients like retinoids or acids for a couple of days.
• Monitor for Any Unusual Symptoms: Report any persistent pain, heat, or skin discoloration to your practitioner.

Following these guidelines helps reduce discomfort and supports a smooth recovery process after Profhilo treatment.

Conclusion

While Profhilo has a strong safety record, patients and providers need to be aware of the full range of potential side effects. Most are mild and temporary, but patients should be informed about rare risks and how to respond appropriately. Safe outcomes rely heavily on experienced injectors, proper patient screening, and clear aftercare instructions. 

By understanding these side effects and their management, both patients and healthcare professionals can ensure a safe and satisfying experience with Profhilo, optimizing both aesthetic results and overall patient well-being.

FAQs

1. How long do Profhilo side effects last?

Most mild side effects, such as swelling or redness, resolve within 24 to 72 hours after treatment.

2. Is Profhilo safe for everyone?

Profhilo is generally safe, but it’s not recommended for pregnant or breastfeeding women or those with specific allergies.

3. Can Profhilo cause allergic reactions?

Although rare, allergic reactions can occur. Symptoms may include itching, rash, or swelling and should be treated promptly.

4. How can I reduce bruising after treatment?

Avoid alcohol, blood thinners, and strenuous activity before and after treatment to help minimize bruising.

5. What should I avoid after getting Profhilo?

Avoid touching the treated area, exercising, and using active skincare ingredients for at least 24–48 hours post-treatment.

6. What happens if a lump appears after treatment?

Small lumps are usually temporary and smooth out within a few days. If they persist, consult your practitioner.

7. When should I seek medical help after Profhilo?

Seek medical attention if you experience prolonged pain, signs of infection, or symptoms like difficulty breathing.

References

Chen D, Yin S, Lu X, Fu H, Gao H, Zhang S. Research on the Correlation Between Skin Elasticity Evaluation Parameters and Age. Cosmetics. 2024;11(6):205-205. doi:https://doi.org/10.3390/cosmetics11060205 

Chaudhary M, Khan A, Gupta M. Skin ageing: Pathophysiology and current market treatment approaches. Current Alzheimer Research. 2020;16(1). doi:https://doi.org/10.2174/1567205016666190809161115